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ACCUPRIL (QUINAPRIL HYDROCHLORIDE): INDICATIONS AND USAGE

Hypertension

Quinapril Hydrochloride (Accupril) tablets are indicated for the treatment of hypertension. It may be used alone or in combination with thiazide diuretics.

Heart Failure

Accupril is indicated in the management of heart failure as adjunctive therapy when added to conventional therapy including diuretics and/or digitalis.

In using Accupril (Quinapril), consideration should be given to the fact that another angiotensin-converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen vascular disease. Available data are insufficient to show that Accupril (Quinapril) tablets does not have a similar risk.

Angioedema in black patients

Black patients receiving ACE inhibitor monotherapy have been reported to have a higher incidence of angioedema compared to non-blacks. It should also be noted that in controlled clinical trials ACE inhibitors have an effect on blood pressure that is less in black patients than in non-blacks.

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